![]() ![]() Formaldehyde, which is in preservatives, cosmetics and other products.Balsam of Peru, which is used in many products, such as perfumes, toothpastes, mouth rinses and flavorings.Nickel, which is used in jewelry, buckles and many other items.Once you develop an allergy to a substance, even a small amount of it can cause a reaction. People often become sensitized to allergens after many contacts with it over years. But it may be triggered by something that enters your body through foods, flavorings, medicine, or medical or dental procedures (systemic contact dermatitis). It often affects only the area that came into contact with the allergen. And some people develop a tolerance to the substance over time.Īllergic contact dermatitis occurs when a substance to which you're sensitive (allergen) triggers an immune reaction in your skin. Others may develop a rash after repeated exposures to even mild irritants, such as soap and water. ![]() Some people react to strong irritants after a single exposure. This nonallergic skin reaction occurs when an irritant damages your skin's outer protective layer. Irritant contact dermatitis is the most common type. Often people have irritant and allergic reactions at the same time. The substance could be one of thousands of known allergens and irritants.
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